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Background
•50-year-old, 60-kg female undergoing elective laparoscopic cholecystectomy for symptomatic gallstone disease
•Previous history of hypertension and currently taking Diovan HCT® (320/25 mg)
•Undergoing hemodialysis for the past 15 years due to chronic kidney failure
•No prior operations or anesthetics
•Planned operation length was approximately 60 minutes
Anesthetic choice
•Induction and intubation were performed with 72 mg propofol and a 1 mcg/kg/min ULTIVA infusion
•Anesthesia was maintained with isoflurane and a 0.25 mcg/kg/min ULTIVA infusion
Perioperative course
•Surgery was uneventful and lasted 54 minutes
•Hemodynamics were stable throughout the procedure
•Patient emerged from anesthesia and was extubated within 10 minutes
•Patient could communicate effectively
•After 125 minutes in the postanesthesia care unit, patient was discharged
•Patient reported headache and transient dizziness (unrelated to a change in hemodynamics) upon emergence that lasted about an hour
In clinical studies of ULTIVA, approximately 10% of patients had a response to skin incision, 50% showed signs of light anesthesia, and 15% responded to skin closure. Hypotension occurred in 16% of patients. Nausea, vomiting, muscle rigidity, and bradycardia were the most common adverse events. Extubation occurred a median of 5 minutes in outpatients and 10 minutes in inpatients. Recovery and discharge times can vary greatly from patient to patient
•50-year-old, 60-kg female undergoing elective laparoscopic cholecystectomy for symptomatic gallstone disease
•Previous history of hypertension and currently taking Diovan HCT® (320/25 mg)
•Undergoing hemodialysis for the past 15 years due to chronic kidney failure
•No prior operations or anesthetics
•Planned operation length was approximately 60 minutes
Anesthetic choice
•Induction and intubation were performed with 72 mg propofol and a 1 mcg/kg/min ULTIVA infusion
•Anesthesia was maintained with isoflurane and a 0.25 mcg/kg/min ULTIVA infusion
Perioperative course
•Surgery was uneventful and lasted 54 minutes
•Hemodynamics were stable throughout the procedure
•Patient emerged from anesthesia and was extubated within 10 minutes
•Patient could communicate effectively
•After 125 minutes in the postanesthesia care unit, patient was discharged
•Patient reported headache and transient dizziness (unrelated to a change in hemodynamics) upon emergence that lasted about an hour
In clinical studies of ULTIVA, approximately 10% of patients had a response to skin incision, 50% showed signs of light anesthesia, and 15% responded to skin closure. Hypotension occurred in 16% of patients. Nausea, vomiting, muscle rigidity, and bradycardia were the most common adverse events. Extubation occurred a median of 5 minutes in outpatients and 10 minutes in inpatients. Recovery and discharge times can vary greatly from patient to patient
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